* Note: Anyone age 60 years or older who does not meet risk-based recommendations may still receive Hepatitis B vaccination. Travel in countries with high or intermediate endemic hepatitis B.Percutaneous or mucosal risk for exposure to blood (e.g., household contacts of HBsAg-positive persons residents and staff of facilities for developmentally disabled persons health care and public safety personnel with reasonably anticipated risk for exposure to blood or blood-contaminated body fluids hemodialysis, peritoneal dialysis, home dialysis, and predialysis patients patients with diabetes).Sexual exposure risk (e.g., sex partners of hepatitis B surface antigen -positive persons sexually active persons not in mutually monogamous relationships persons seeking evaluation or treatment for a sexually transmitted infection men who have sex with men).Chronic liver disease (e.g., persons with hepatitis C, cirrhosis, fatty liver disease, alcoholic liver disease, autoimmune hepatitis, alanine aminotransferase or aspartate aminotransferase level greater than twice upper limit of normal).Age 60 years or older* and at risk for hepatitis B virus infection: 2-dose (Heplisav-B) or 3-dose (Engerix-B, Recombivax HB) series or 3-dose series HepA-HepB (Twinrix) as above. ![]() Settings for exposure, including health care settings targeting services to injection or noninjection drug users or group homes and nonresidential day care facilities for developmentally disabled persons (individual risk factor screening not required).Pregnancy if at risk for infection or severe outcome from infection during pregnancy.Close, personal contact with international adoptee (e.g., household or regular babysitting) in first 60 days after arrival from country with high or intermediate endemic hepatitis A (administer dose 1 as soon as adoption is planned, at least 2 weeks before adoptee’s arrival). ![]()
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